Epidemiological study on the association between obesity with metabolic syndrome in obese children and adolescents of Nanning city, Guangxi
10.3760/cma.j.issn.0254-6450.2011.10.004
- VernacularTitle:南宁地区儿童青少年肥胖与代谢综合征相关性的流行病学研究
- Author:
Shao-Ke CHEN
1
;
Jing-Si LUO
;
Ying-Fen QIN
;
Xin FAN
;
Qing TANG
;
Ying FENG
Author Information
1. 广西壮族自治区妇幼保健院
- Keywords:
Obesity;
Metabolic syndrome;
Risk factor
- From:
Chinese Journal of Epidemiology
2011;32(10):969-972
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between obesity and prevalence of metabolic syndrome (MS) with its associated risk factors,in children and adolescents.Methods A stratified random sampling method was used to select 7893 students from 6 to 18 years of age from 14 out of 396 primary and secondary schools in Nanning city.All the students had undergone physical examination and blood tests including the following risk factors related to metabolic syndrome:fasting blood glucose (FBG),total cholesterol (TC),triglycerides (TG),high-density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol (LDL-C),alanine amino shift enzyme (ALT),aspartic acid amine shift enzyme (AST) and fasting insulin (FINS).The homeostasis model assessment insulin resistance index (HOMA-IR) was also measured.Results (1) The prevalence rate of MS in normal group was 0.57％.In both the overweight and obesity groups,the prevalence rates of MS were 4.53％ and 26.80％,respectively.(2) These indices in obesity group were higher than other two groups (P＜0.05).The result of overweight group was higher than normal group (P＜0.05).(3) Waist circumference(OR=1.087,95％CI:1.033-1.143 ),SBP ( OR=1.073,95％CI:1.032-1.116),FBG (OR=1.394,95％CI:1.568-3.423),TG (OR=3.213,95％CI:1.410-7.319) and HDL-C (OR=0.001,95％CI:0.000-0.012)were detecting indices which had statistically significant with MS in binary logistic regression analysis.Conclusion Metabolic syndrome and obesity were closely related in children and adolescents while its prevalence and risk factors increased with the severity of obesity.
