A sero-epidemiological study on hepatitis C in China
10.3760/cma.j.issn.0254-6450.2011.09.009
- VernacularTitle:中国丙型肝炎血清流行病学研究
- Author:
Yuan-Sheng CHEN
1
;
Li LI
;
Fu-Qiang CUI
;
Wen-Ge XING
;
Lu WANG
;
Zhi-Yuan JIA
;
Mai-Geng ZHOU
;
Xiao-Hong GONG
;
Fu-Zhen WANG
;
Hui ZHENG
;
Hui-Ming LUO
;
Sheng-Li BI
;
Ning WANG
;
Wei-Zhong YANG
;
Xiao-Feng LIANG
Author Information
1. 中国疾病预防控制中心
- Keywords:
Hepatitis C;
Sero-epidemiology
- From:
Chinese Journal of Epidemiology
2011;32(9):888-891
- CountryChina
- Language:Chinese
-
Abstract:
Objective To better understand and measure the status of hepatitis C virus (HCV) infection, we conducted a sero-epidemiological study using the remaining blood samples and data of the nationwide survey of hepatitis B in Chinese residents which was carried out in 2006.Methods The anti-HCV reagent was screened out from the reagents by the HCV infection blood serum plate with anti-HCV positives or negatives. This plate recognized the Murex 3.0 and Ortho 3.0 reagents as gold standards. Anti-HCV in the blood samples were tested using this reagent and confirmed by Chiron HCV RIBA 3.0 reagents. Results Among the population aged 1 year to 59 year-olds, the overall prevalence rate of anti-HCV was 0.43% (95%CI: 0.33%-0.53% ), with the rates of anti-HCV among males and females as 0.46% and 0.40%, respectively. The prevalence rate of anti-HCV in urban area was 0.43%,and in rural area it was 0.43%. The prevalence rate of anti-HCV in the Eastern, Middle and Western areas were 0.37% (95% CI: 0.21%-0.53% ) , 0.67% (95% CI: 0.40%-0.94% ) and 0.31% (95%CI: 0.20%-0.42% ) respectively. The prevalence rates of anti-HCV for the three areas did not show significant differences, statistically. The prevalence rate of anti-HCV in the South and North areas were 0.29%(95%CI:0.21%-0.52%) and 0.53% (95%CI:0.38%-0.64%)respectively. Conclusion Our data revealed that China was in the low prevalence area for hepatitis C infection and the results also suggested that the comprehensive measures for HCV control and prevention had been successfully achieved in the country.