Study on prevention and treatment of radiotherapy caused post-visual pathway injury in nasopharyngeal carcinoma patients by traditional Chinese medicine.
- Author:
Bo-ping XU
1
;
Shi-xian LONG
;
Wei-han HU
Author Information
- Publication Type:Clinical Trial
- MeSH: Adult; Drugs, Chinese Herbal; therapeutic use; Evoked Potentials, Visual; Female; Humans; Male; Middle Aged; Nasopharyngeal Neoplasms; drug therapy; radiotherapy; Phytotherapy; Radiation Injuries; prevention & control; Visual Pathways; injuries
- From: Chinese Journal of Integrated Traditional and Western Medicine 2003;23(9):661-663
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of TCM in preventing and treating post-visual pathway injury caused by radiotherapy (RT) for nasopharyngeal carcinoma (NPC).
METHODSThirty-five patients of NPC were randomly divided into the RT group (n = 17) and the RT + TCM group (n = 18), they were all received RT, but the latter was treated additionally with Jingming recipe, a Chinese recipe. The latent period and amplitude of evoked potential (EP) were measured before and after ending of RT, using multi-focusing visual evoked potential inspector.
RESULTSThe latent time of EP, both upper and lower visual field, was prolonged significantly after RT in the RT group (P < 0.05), but not in the RT + TCM group (P > 0.05); the amplitude of EP of upper visual field lowered significantly (P < 0.05) in the RT group but insignificantly in the RT + TCM group (P > 0.05); as for the EP amplitude of lower visual field, it was unaltered in RT group after RT (P > 0.05), but increased in the RT + TCM group (P < 0.05).
CONCLUSIONThe Chinese medicine Jingming recipe was effective in preventing and treating RT induced post-visual pathway injury.
