Clinical study on effect of yuantong capsule in treating vascular dementia.
- Author:
Jun-shan HUANG
1
;
Qiu-cheng LIN
;
Rong-zhang HUANG
Author Information
- Publication Type:Clinical Trial
- MeSH: Aged; Aged, 80 and over; Capsules; Dementia, Vascular; drug therapy; Drug Therapy, Combination; Drugs, Chinese Herbal; therapeutic use; Ergoloid Mesylates; therapeutic use; Female; Humans; Male; Middle Aged; Nootropic Agents; therapeutic use; Phytotherapy
- From: Chinese Journal of Integrated Traditional and Western Medicine 2003;23(11):815-818
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the clinical effect of Yuantong Capsule (YTC) in treating vascular dementia (VD).
METHODSEighty-three patients of VD were randomized on ratio of 2:1 into two groups, the 54 patients in the treated group were treated with YTC orally administered, 3 times a day, 1 capsule in each time. The remaining 29 patients in the control group were treated with Hydergine orally, 3 times a day, 2 mg in each time. The therapeutic course for both groups was 2 months.
RESULTSThe therapeutic effect in the treated group was significantly better than that in the control group, significant difference (P < 0.05 or P < 0.01) was shown in comparison of the two groups in terms of the mini-mental state examination (MMSE) and activity of daily living (ADL) test, symptoms scoring, total effective rate, and laboratory indexes findings.
CONCLUSIONThe therapeutic effect of YTC in treating VD was obvious.