Expression of angiopoietin-like proteins for animal breeding: a review.
- Author:
Weiwei FU
;
Yun MA
;
Ningbo CHEN
;
He LI
;
Yueyu BAI
- Publication Type:Journal Article
- MeSH:
Angiopoietins;
genetics;
metabolism;
Animals;
Breeding;
Energy Metabolism;
Gene Regulatory Networks;
Glucose;
metabolism;
Lipid Metabolism;
Metabolic Networks and Pathways;
Signal Transduction
- From:
Chinese Journal of Biotechnology
2015;31(11):1567-1578
- CountryChina
- Language:Chinese
-
Abstract:
Angiopoietin-like proteins are a family of proteins that are closely related to lipid, glucose and energy metabolism, as well as angiogenesis. To date, eight Angptls have been discovered, namely Angptl1 to Angptl8 that play key roles in metabolic regulation and marker assisted selection. In this review, we summarized current progress on the structure, signaling pathways, upstream regulatory genes and metabolic network of Angptl1-8. Finally, in combination with our work, the status and problems of animal breeding as well as the future prospects for Angptls were discussed.
