A Case of Neuropsychiatric Lupus Presenting as Guillain-Barre Syndrome and Cerebral Infarction.
- Author:
Hyun Seung KIM
1
;
Seung Chan LEE
;
Hyun Il HONG
;
Koon Hee HAN
;
Soon Keum LEE
;
Sung Soo KIM
Author Information
1. Division of Rheumatology, Departments of Internal Medicine Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea. drkiss@gnah.co.kr
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Neuropsychiatric lupus;
Guillain-Barre syndrome;
Cerebral infarction
- MeSH:
Adult;
Anticoagulants;
Antigen-Antibody Complex;
Autoantibodies;
Cerebral Infarction*;
Cyclophosphamide;
Female;
Guillain-Barre Syndrome*;
Humans;
Immunoglobulins;
Lupus Erythematosus, Systemic;
Methylprednisolone;
Nervous System;
Rheumatology
- From:The Journal of the Korean Rheumatism Association
2004;11(4):411-416
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic lupus erythematosus (SLE) is a disease of unknown etiology in which tissues and cells damaged by pathogenic autoantibodies and immune complexes. Nervous system involvement in patients with SLE encompasses a wide spectrum of neurologic and psychiatric features and the frequency of neuropsychiatric manifestations has been estimated at around 25% to 70%. American College of Rheumatology Ad Hoc Committee on neuropsychiatric lupus nomenclature developed case definitions for 19 different neuropsychiatric manifestations observed in SLE in 1999. Among them, Guillain-Barre syndrome and cerebral infarction are very rare neuropsychiatric manifestation. We experienced a 28-year-old woman with neuropsychiatric lupus which presented as Guillain-Barre syndrome and cerebral infarction. She was recovered after treatment with intravenous immunoglobulin, high dose methylprednisolone, cyclophosphamide and anticoagulants.
