Scanning electron microscopic study of titanium-hydroxyapatite, the functionally graded-material implanted in rabbits.
- Author:
Xiao-jun TANG
1
;
Shu-zhong XING
;
Xiao-ling SONG
;
Lai GUI
;
Cheng-lin CHU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Bone Substitutes; chemistry; Female; Hydroxyapatites; chemistry; Male; Materials Testing; Microscopy, Electron, Scanning; Osseointegration; Rabbits; Titanium; chemistry
- From: Chinese Journal of Plastic Surgery 2005;21(6):415-417
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEThe purpose of this study was to observe the tissue tolerance of Ti-HA functionally graded-material (FGM) and the form of the material-bone interface.
METHODSThe sintered Ti -HA FGM, pure HA and pure Ti were respectively implanted into the parietal bone of rabbits. The specimens were observed by SEM at 2, 4, 8 postoperative weeks.
RESULTSIn the early stage, the new bone surrounding the Ti -HA FGM formed earlier with larger amount and better maturity than the pure Ti. The condition was similar to the pure HA. Two months after the operation, direct bonding of material-bone interface was formed between the Ti -HA FGM and the new bone as an integral body. However, there was a little space left between the new bone and the pure Ti.
CONCLUSIONSThe Ti -HA FGM has good tissue tolerance. Its early integration with bone is similar to pure HA and better than pure Ti.
