Estimation of hospitalization rate of laboratory confirmed influenza cases in Jingzhou city, Hubei province, 2010-2012.

Jiandong Zheng; Hui Chen; Maoyi Chen; Yang Huai; Hui Jiang; Xuesen Xing; Zhibin Peng; Nijuan Xiang; Yuzhi Zhang; Linlin Liu; Jigui Huang; Luzhao Feng; Xuhua Guan; John Klena; Faxian Zhan; Hongjie YU; Email: Yuhj@chinacdccn

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Estimation of hospitalization rate of laboratory confirmed influenza cases in Jingzhou city, Hubei province, 2010-2012.

Author: Jiandong ZHENG ¹ ; Hui CHEN ² ; Maoyi CHEN ³ ; Yang HUAI ⁴ ; Hui JIANG ¹ ; Xuesen XING ² ; Zhibin PENG ¹ ; Nijuan XIANG ⁵ ; Yuzhi ZHANG ⁴ ; Linlin LIU ² ; Jigui HUANG ³ ; Luzhao FENG ¹ ; Xuhua GUAN ² ; John KLENA ⁴ ; Faxian ZHAN ² ; Hongjie YU ⁶ ; Email: YUHJ@CHINACDC.CN.
Author Information

1. Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
2. Hubei Provincial Center for Disease Control and Prevention.
3. Jingzhou Center for Disease Control and Prevention.
4. China-United States Collaborative Program on Emerging and Re-emerging Infectious Diseases, United States Center for Disease Control and Prevention.
5. Public Health Emergency Center, Chinese Center for Disease Control and Prevention.
6. Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Publication Type:Journal Article
MeSH: Child; Child, Preschool; China; epidemiology; Demography; Hospitalization; Hospitals; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; epidemiology; Inpatients; Laboratories; Orthomyxoviridae; Polymerase Chain Reaction; Respiratory Tract Infections; Seasons; Vaccination
From: Chinese Journal of Epidemiology 2015;36(3):222-227
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo estimate the hospitalization rate of severe acute respiratory infection (SARI) cases attributable to influenza in Jingzhou city, Hubei province from 2010 to 2012.
METHODSSARI surveillance was conducted at four hospitals in Jingzhou city, Hubei province from 2010 to 2012. Inpatients meeting the SARI case definition and with informed consent were enrolled to collect their demographic information, clinical features, treatment, and disease outcomes, with their respiratory tract specimens collected for PCR test of influenza virus.
RESULTSFrom April, 2010 to September, 2012, 19 679 SARI cases enrolled were residents of Jingzhou, and nasopharyngeal swab was collected from 18 412 (93.6%) cases of them to test influenza virus and 13.3% were positive for influenza. During the three consecutive 2010-2012 flu seasons, laboratory-confirmed influenza was associated with 102 per 100 000, 132 per 100 000 and 244 per 100 000, respectively. As for the hospitalization rate attributable to specific type/subtype of influenza virus, 48 per 100 000, 30 per 100 000 and 24 per 100 000 were attributable to A (H3N2), A (H1N1) pdm2009, and influenza B, respectively in 2010-2011 season; 42 per 100 000 [A (H3N2)] and 90 per 100 000 (influenza B) in 2011-2012 season; 90 per 100 000 [A (H3N2)] and one per 100 000 [influenza B] from April, 2010 to September, 2012. SARI hospitalization caused by influenza A or B occurred both mainly among children younger than five years old, with the peak in children aged 0.5 year old.
CONCLUSIONInfluenza could cause a substantial number of hospitalizations and different viral type/subtype result in different hospitalizations over influenza seasons in Jingzhou city, Hubei province. Children less than five years old should be prioritized for influenza vaccination in China.