Clinical features of pure erythroid leukemia--case report and review of literature.
- Author:
Yan-Ming ZHANG
1
;
De-Pei WU
;
Yu-Mei SUN
;
Shu-Hua LU
;
Ming-Qing ZHU
Author Information
- Publication Type:Case Reports
- MeSH: Humans; Leukemia, Erythroblastic, Acute; therapy; Male; Middle Aged; Prognosis
- From: Chinese Journal of Hematology 2008;29(5):293-295
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo report a case of pure erythroid leukemia.
METHODSThe clinical features, treatment and prognosis of a rare case of pure erythroid leukemia were reported, and the related literature was reviewed.
RESULTSThe pure erythroid leukemia patient was diagnosed by 90.4% pronormoblasts in bone marrow, 99.5% for erythroid antigen CD71, 67.4% for glycophorin A were detected, while no differentiation antigen of myeloid, lymphoid and megakaryocyte lineages were observed. HAG (homoharringtonine + Cytarabine and G-CSF) regimen were administered with no effect. The patient developed multiple organ failure and died soon.
CONCLUSIONPure erythroid leukemia has a fulminant clinical course with poor response to chemotherapy and worse prognosis.