FK-506 ointment: an effective adjuvant therapy to treat a dramatic case of pyoderma gangrenosum of unilateral hand.
- Author:
Stefano LUCCHINA
1
;
Sandra Leoni PARVEX
;
Paul BIEGGER
;
Cesare FUSETTI
Author Information
1. Hand Surgery Unit, Surgical Department, Locarno's Regional Hospital, Via all'Ospedale 1 6600, Locarno, Switzerland. stefano.lucchina@handregistry.com
- Publication Type:Case Reports
- MeSH:
Aged;
Hand;
Humans;
Male;
Ointments;
Pyoderma Gangrenosum;
drug therapy;
pathology;
Tacrolimus;
administration & dosage
- From:
Chinese Journal of Traumatology
2009;12(3):181-183
- CountryChina
- Language:English
-
Abstract:
Pyoderma gangrenosum (PG) is a cutaneous ulcer developing so rapidly that may mimic a fulminating infection. The correct treatment is nonsurgical, and surgery may get the condition worse.1 FK-506 ointment (0.1% Protopic, Astellas Pharma AG, Fribourg) is usually indicated for inflammatory skin diseases, such as atopic dermatitis and psoriasis2 or for acute rejection reversal of human hand transplantation 3. A few reports of PG affecting the functions of hands can be found in the scientific literature and this report describes the first case treated by FK-506 ointment as an adjuvant therapy.