Influence of Minkeqing oral liquid on IL-6, IL-8, ET-1, TX-B2 in blood and to observe bronchoalveolar lavage fluid of the rat with inhalating ovalbumin.
- Author:
Shan ZHU
1
;
Wen-Sheng ZHAI
;
Xiang-Yun LI
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Bronchoalveolar Lavage Fluid; chemistry; Cough; blood; chemically induced; metabolism; Drug Combinations; Drugs, Chinese Herbal; isolation & purification; pharmacology; Endothelin-1; blood; metabolism; Hypersensitivity; blood; metabolism; Interleukin-6; blood; metabolism; Interleukin-8; blood; metabolism; Male; Ovalbumin; Plants, Medicinal; chemistry; Random Allocation; Rats; Rats, Wistar; Thromboxane B2; blood; metabolism
- From: China Journal of Chinese Materia Medica 2005;30(14):1099-1102
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effect on infantile allergic cough with Minkeqing oral liquid (Minkeqing) and to study its cell molecular biologic mechanism.
METHODThe rat model was induced by inhalating ovalbumin; then the effects of Minkeqing on IL-6, IL-8, ET-1, TX-B2 in the blood and the bronchoalveolar lavage fluid (BALF) of the animal model were observed.
RESULTMinkeqing could reduce the levels of IL-6,IL-8,ET-1,Tx-B2 in the blood and BALF of the animal model.
CONCLUSIONMinkeqing has the significant function of inhibiting the release of inflammatory mediums.
