Effects of the volatile oil of Centipeda minima on acute pleural effusion in rats induced by an intrapleural injection of car.
- Author:
Ren-An QIN
1
;
Xuan MEI
;
Lei WAN
;
Jing-Li SHI
;
Ying-Jun SHEN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Asteraceae; chemistry; C-Reactive Protein; metabolism; Carrageenan; Dinoprostone; metabolism; Interleukin-8; blood; Leukocyte Count; Male; Nitric Oxide; metabolism; Oils, Volatile; isolation & purification; pharmacology; Plants, Medicinal; chemistry; Pleural Effusion; chemically induced; metabolism; pathology; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; blood
- From: China Journal of Chinese Materia Medica 2005;30(15):1192-1194
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the anti-inflammation effect of volatile oil of Centipeda minima and the mechanism of action.
METHODThe animal model was induced by the Car injection into intrapleural of rats, to observe the effect of VOCM on acute inflammation.
RESULTVOCM was able to inhibit the increase of NO, CRP and proinflammatory cytokines such as TNFalpha in the acute inflammation of the rat body.
CONCLUSIONVOCM has a protective effect on acute pleural effusion in rats induced by an intrapleural injection of Car.
