Research progress in the reversion of traditional Chinese medicine on multidrug resistance of tumor.
- Author:
Xiang-rong SONG
1
;
Shi-xiang HOU
Author Information
1. West China College of Pharmacy, Sichuan University, Chengdu 610041, China.
- Publication Type:Journal Article
- MeSH:
ATP-Binding Cassette, Sub-Family B, Member 1;
biosynthesis;
genetics;
Animals;
Breast Neoplasms;
metabolism;
Carcinoma, Hepatocellular;
metabolism;
DNA Topoisomerases, Type II;
metabolism;
Drug Combinations;
Drug Resistance, Multiple;
drug effects;
Drug Resistance, Neoplasm;
drug effects;
Drugs, Chinese Herbal;
isolation & purification;
pharmacology;
Genes, MDR;
Humans;
Leukemia;
metabolism;
Liver Neoplasms;
metabolism;
Medicine, Chinese Traditional;
Multidrug Resistance-Associated Proteins;
metabolism;
Plants, Medicinal;
chemistry;
RNA, Messenger;
biosynthesis;
genetics
- From:
China Journal of Chinese Materia Medica
2005;30(16):1300-1304
- CountryChina
- Language:Chinese
-
Abstract:
Researches on MDR (multidrug resistance) of tumor presently focus on seeking chemosensitizers with more targets, high efficiency and low toxicity from traditional Chinese medicine. This paper reviews the research progress in the reversion of MDR of leukemia, hepatocarcinoma, breast carcinoma and oral epithelioid neoplasia by TDM compound, its extracts, its groups of active ingredients or its active ingredients.
