Comparative studies on pharmacological effects of the main chemical constituents of Peucedanum praeruptorum from He'nan and Jiangxi.
- Author:
Cun ZHANG
1
;
Wen LI
;
Yong-qing XIAO
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Anti-Inflammatory Agents, Non-Steroidal; isolation & purification; pharmacology; Antitussive Agents; isolation & purification; pharmacology; Apiaceae; chemistry; China; Coumarins; isolation & purification; pharmacology; Drugs, Chinese Herbal; chemistry; Female; Male; Mice
- From: China Journal of Chinese Materia Medica 2005;30(17):1356-1358
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo compare the pharmacological effect of the main coumarin constituents of Peucedanum praeruptorum from Jiangxi and He'nan.
METHODThe constituents were isolated by column chromatography on silica gel and ODS and identified by NMR and MS spectroscopic methods. The antitussive, expectorant and anti-inflammatory effects of main coumarin constituents of P. praeruptorum observed in the present study.
RESULTThe main constituents of P. praeruptorum from both Jiangxi and He'nan showed the significant antitussive and anti-inflammatory effects without obviously expectorant effect.
CONCLUSIONThe pharmacological effects of the main coumarin constituents of Qian-hu from Jiangxi and He'nan are similar.
