Zijin powder in inhibiting H22 mice solid and ascites liver cancer: experimental study.
- Author:
Da-wen WEI
1
;
Yu-mei JIA
;
Zhong-zheng LI
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Antineoplastic Agents, Phytogenic; pharmacology; therapeutic use; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; pharmacology; Female; Humans; Liver Neoplasms; drug therapy; Male; Mice; Phytotherapy; Powders; Random Allocation
- From: China Journal of Chinese Materia Medica 2005;30(17):1346-1348
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the rate of Zijin powder in inhibiting H22 mice solid and ascites liver cancer and the relation between quatity and effect.
METHODThe Kunming mics, transplanted by H22 liver cells, were divided into a model group, a cyclophosphamide group and three groups of Zijin powder in high dose, medium dose, and low dose. Then observation was made on the rate of Cancer.
RESULTThe inhibiting rates of Zijin powder of three groups (high dose group, medium dose group and low dose group) for H22 mice solid liver cancer were 30.8%, 38.31% and 48.59% respectivily. The inhibiting rates of three groups of Zijin powder (low dose group, medium dose and high dose group) for H22 mice ascites liver cancer were 6.77%, 15.59% and 14.90 % respectivily.
CONCLUSIONZijin powder has better effect on H22 mice solid liver cancer, and its effect is greatly increasing with the increased dosage.