Studies on the chemical constituents in root of Gentiana macrophylla from Shaanxi.
- Author:
Qian-Liang CHEN
1
;
Zhang-Yan SHI
;
Guang-Zhong TU
;
Wen-Ji SUN
Author Information
- Publication Type:Journal Article
- MeSH: Gentiana; chemistry; Glucosides; chemistry; isolation & purification; Iridoid Glucosides; Iridoids; chemistry; isolation & purification; Isocoumarins; chemistry; isolation & purification; Molecular Structure; Plant Roots; chemistry; Plants, Medicinal; chemistry
- From: China Journal of Chinese Materia Medica 2005;30(19):1519-1522
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo in vestigate the constituents in root of Gentiana macrophylla.
METHODVarious column chromatographic techniques were used for isolation and purification of the principles. The structures were elucidated on the basis of spectral data (UV, IR, MS, 1H-, 13C-NMR etc.) and identified by comparing with standard substance.
RESULTEight compounds were identified. Four compounds isolated from the chloroform fraction are: 5-carboxyl-3,4-dihydrogen-1H-2-benzopyran-1-one (1), erythrocentauric acid (2), roburic acid (3), oleanolic acid (4). Water fraction gave four known secoiridoid glucosides. They were: gentiopicroside (5), swertiamarine (6), sweroside (7), 6'-O-beta-D-glucosylgentiopicroside (8).
CONCLUSION1 is a novel compound. It was named as erythrocentauric acid. 2 was isolated from genus Gentiana and 8 was isolated from G. macrophylla for the first time.
