The effect of muscovite on the quality of gastric ulcer healing.
- Author:
Jian-Min SI
1
;
Yun QIAN
;
Jia-Guo WU
Author Information
- Publication Type:Journal Article
- MeSH: Aluminum Silicates; pharmacology; Animals; Dinoprostone; blood; Fibroblast Growth Factor 2; metabolism; Gastric Mucosa; pathology; physiopathology; Hexosamines; metabolism; Male; Materia Medica; pharmacology; Mucus; secretion; Rats; Rats, Wistar; Receptor, Epidermal Growth Factor; metabolism; Stomach Ulcer; chemically induced; pathology; physiopathology
- From: China Journal of Chinese Materia Medica 2005;30(19):1536-1541
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the effect of muscovite on the quality of gastric ulcer healing.
METHODGastric ulcers were produced in male rats by serosal application of acetic acid. Rats were gavaged for 14 days with saline, omeprazole and muscovite starting 3 days after ulcer induction. Then the tissue and blood samples were obtained and measured.
RESULTIn the muscovite group, restored mucosa thickness increased, cystically dilated glands decreased, microvessels in connective tissue increased, the secretion of mucus, hexosamine, PGE2, EGF, bFGF were enhanced, and the express of EGFR was stronger.
CONCLUSIONMuscovite can promote the gastric ulcer healing and improve the quality of gastric ulcer healing.
