Research advances of anti-tumor immune response induced by pulse electric field ablation.
- Author:
Guang-ying CUI
1
;
Hong-yan DIAO
1
Author Information
1. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, Zhejiang University School of Medicine, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou 310003, China.
- Publication Type:Journal Article
- MeSH:
Ablation Techniques;
Electricity;
Humans;
Neoplasms;
immunology;
therapy
- From:
Journal of Zhejiang University. Medical sciences
2015;44(6):672-677
- CountryChina
- Language:Chinese
-
Abstract:
As a novel tumor therapy, pulse electric field has shown a clinical perspective. This paper reviews the characteristics of tumor ablation by microsecond pulse and nanosecond pulse electric field, and the research advances of anti-tumor immune response induced by pulse electric field ablation. Recent researches indicate that the pulse electric field not only leads to a complete ablation of local tumor, but also stimulates a protective immune response, thereby inhibiting tumor recurrence and metastasis. These unique advantages will show an extensive clinical application in the future. However, the mechanism of anti-tumor immune response and the development of related tumor vaccine need further studies.
