Research progress on application of carbon nanotubes in bone tissue engineering scaffold.
- Author:
Mengzhu YAO
1
;
Xiaoxia SHENG
2
;
Jun LIN
3
;
Jianqing GAO
4
Author Information
1. Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
2. Hangzhou Solipharma Co. Ltd, Hangzhou 310058,China.
3. Department of Stomatology,the First Affiliated Hospital,Zhejiang University School of Medicine, Hangzhou 310009, China.
4. Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. gaojianqing@zju.edu.cn.
- Publication Type:Journal Article
- MeSH:
Biocompatible Materials;
chemistry;
Bone Development;
Humans;
Microspheres;
Nanotubes, Carbon;
chemistry;
Polymers;
chemistry;
Printing, Three-Dimensional;
Tissue Engineering;
Tissue Scaffolds;
chemistry
- From:
Journal of Zhejiang University. Medical sciences
2016;45(2):161-169
- CountryChina
- Language:Chinese
-
Abstract:
Carbon nanotubes possess excellent mechanical and electrical properties and demonstrate broad application prospects in medical fields. Carbon nanotubes are composed of inorganic materials, natural biodegradable polymer or synthetic biodegradable polymer. The composite bone tissue engineering scaffolds are constructed by particle-hole method, lyophilization, microsphere aggregation method, electrostatic spinning or three-dimensional printing. Composite scaffolds overcome the shortcomings of single material and have good biocompatibility, osteoconduction and osteoinduction. With the study of surface chemistry, toxicology, and biocompatibility, a degradable "human-friendly" carbon nanotubes composite bone tissue scaffold will be available; and under the drive of new fabrication techniques, the clinical application of carbon nanotubes composite bone tissue engineering scaffolds will be better developed.
