Research progress on the role of epithelial-mesenchymal transition in pathogenesis of endometriosis.
- Author:
Tianhong ZHU
1
;
Xinmei ZHANG
2
Author Information
1. Department of Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
2. Department of Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China. zxm20130729@163.com.
- Publication Type:Journal Article
- MeSH:
Endometriosis;
complications;
etiology;
pathology;
physiopathology;
Epithelial-Mesenchymal Transition;
physiology;
Female;
Fibrosis;
complications;
Humans;
Inflammation;
complications;
Signal Transduction;
physiology
- From:
Journal of Zhejiang University. Medical sciences
2016;45(4):439-445
- CountryChina
- Language:Chinese
-
Abstract:
Epithelial-mesenchymal transition plays an important role in the development and progression of endometriosis. Mesenchymal-epithelial transition is involved in forming localized lesions of endometriosis, while EMT is involved in the injury, repair and fibrosis induced by local inflammation of endometriosis and the process of cell invasion and metastasis. The studies of signal transduction pathway and related proteins of epithelial-mesenchymal transition in the process of endometriosis may provide new targets for diagnosis and treatment of endometriosis.
