Hemophagocytic Syndrome Associated with Kikuchi's Disease.
10.3346/jkms.2003.18.4.592
- Author:
Young Mi KIM
1
;
Yoon Jin LEE
;
Sang Ook NAM
;
Su Eun PARK
;
Ji Yoen KIM
;
Eun Yup LEE
Author Information
1. Department of Pediatrics, College of Medicine, Pusan National University, Busan, Korea. pse0731@hanmail.net
- Publication Type:Case Report
- Keywords:
Histiocytic Necrotizing Lymphadenitis;
Kikuchi's Disease;
Histiocytosis
- MeSH:
Adolescent;
Adrenal Cortex Hormones/therapeutic use;
Biopsy;
Bone Marrow Cells/metabolism/pathology;
Female;
Ferritin/blood;
Histiocytic Necrotizing Lymphadenitis/*complications/*diagnosis;
Histiocytosis, Non-Langerhans-Cell/*complications/*diagnosis;
Human;
Immunoglobulins/metabolism/therapeutic use;
L-Lactate Dehydrogenase/blood;
Lymph Nodes/pathology;
Lymphatic Diseases/diagnosis;
Necrosis;
Pancytopenia/diagnosis;
Prognosis;
Transaminases/blood;
Triglycerides/blood
- From:Journal of Korean Medical Science
2003;18(4):592-594
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 13-yr-old female was admitted to our hospital with fever, seizure, and cervical lym-phadenopathy. Laboratory data showed pancytopenia, elevation of serum transaminase, lactate dehydrogenase, triglyceride, and ferritin levels. Lymph node biopsy revealed features of Kikuchi's disease and there were signs of histiocytosis and hemophagocytic phenomenon in bone marrow. She recovered after treatment with intravenous immunoglobulin and corticosteroids therapy. Hemophagocytic syndrome can be associated with Kikuchi's disease especially in childhood and seems to have a less aggressive clinical course and better prognosis.
