Sjogren's Syndrome Presenting as Remitting Seronegative Symmetric Synovitis with Pitting Edema(RS3PE).
10.3346/jkms.2003.18.4.606
- Author:
Young Mi CHOI
1
;
Dong Hyuk SHEEN
;
Yun Jong LEE
;
Eun Bong LEE
;
Yeong Wook SONG
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Medical Research Center, Seoul National University Hospital, Seoul, Korea. ysong@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Sjogren's Syndrome;
Synovitis;
Edema;
RS3PE
- MeSH:
Adult;
Antibodies, Antinuclear/biosynthesis;
Arthritis/complications;
Biopsy;
Blood Sedimentation;
Diagnosis, Differential;
Edema/*diagnosis;
Female;
Human;
Lymphocytes/pathology;
Prednisolone/therapeutic use;
Rheumatoid Factor/biosynthesis;
Salivary Glands/pathology;
Sjogren's Syndrome/*diagnosis;
Syndrome;
Synovitis/*diagnosis
- From:Journal of Korean Medical Science
2003;18(4):606-608
- CountryRepublic of Korea
- Language:English
-
Abstract:
Remitting seronegative symmetric synovitis with pitting edema (RS3 PE) syndrome is characterized by symmetrical and acute synovitis, pitting edema, the absence of rheumatoid factor, increased acute phase reactants, lack of bony erosions on radiography, and benign and short clinical course. Half of all patients with Sjogren's syndrome experience arthritis during the disease course. We here describe the first case of Sjogren's syndrome presenting as RS3PE. She had swelling in knees, ankles, and wrists. After then the swelling spread to her lower legs, feet, face, and both hands. She was admitted to another hospital and was suspected of lupus or rheumatoid arthritis. Three months later, she had dry mouth and had lower lip biopsy. She was admitted to this hospital due to development of swelling in face and lower legs for 3 days. On physical examination, she had pitting edema in both hands and feet dorsum. Laboratory test showed elevated erythrocyte sedimentation rate, positivity of rheumatoid factor, anti-nuclear antibody, and anti-Ro antibody. There was no erosion in the hands radiography. Schirmer's test and lip biopsy was compatible with Sjogren's syndrome. She was diagnosed RS3 PE and Sjogren's syndrome. She was begun with prednisolone and her symptoms improved gradually.
