Advances in research on gastrointestinal cancer-associated long non-coding RNAs.
10.3760/cma.j.issn.1003-9406.2015.02.029
- VernacularTitle:胃肠道肿瘤相关长链非编码RNA研究进展
- Author:
Jiaxin GE
1
;
Qianqian PANG
;
Junming GUO
Author Information
1. Department of Biochemistry and Molecular Biology, Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, Ningbo, Zhejiang 315211, P. R. China. guojunming@nbu.edu.cn.
- Publication Type:Journal Article
- MeSH:
Animals;
Gastrointestinal Neoplasms;
genetics;
metabolism;
Gene Expression Regulation, Neoplastic;
Humans;
RNA, Long Noncoding;
genetics;
metabolism
- From:
Chinese Journal of Medical Genetics
2015;32(2):284-287
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNAs (lncRNAs) are a class of non-coding transcripts which are greater than 200 nucleotides in length and have a variety of biological functions. Studies have found that lncRNAs play an important role in the development of gastrointestinal cancers and can affect tumor cell growth, angiogenesis, metastasis and drug resistance. This paper has reviewed lncRNAs associated with gastrointestinal cancers and explored their roles in the occurrence, diagnosis and treatment of gastrointestinal cancers.
