Patients selection and response evaluation in neoadjuvant chemoradiation of rectal cancer.
- Author:
Lijun SHEN
1
;
Zhen ZHANG
Author Information
1. Department of Radiation Oncology, Cancer Hospital, Fudan University, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China. zhenzhang6@gmail.com.
- Publication Type:Editorial
- MeSH:
Chemoradiotherapy;
Humans;
Neoadjuvant Therapy;
Patient Selection;
Prognosis;
Rectal Neoplasms;
therapy
- From:
Chinese Journal of Gastrointestinal Surgery
2014;17(3):201-205
- CountryChina
- Language:Chinese
-
Abstract:
Neoadjuvant chemoradiation combined with radical surgery has been established as the standard care for locally advanced rectal cancer(T3-T4 and/or N1-N2). Approximately 20% patients who achieve complete pathological response have an improved prognosis. Appropriate patient selection may help avoid over-treatment. Evaluation of treatment response mostly with imaging study and pathology after neoadjuvant chemoradiation and following surgery is essential for the subsequent selection of treatment strategy.
