Comprehensive application of CT and PET/CT in diagnosing colorectal mucinous and non-mucinous adenocarcinoma.
- Author:
Siyun HUANG
1
;
Canhui SUN
;
Xuehua LI
;
Jian GUAN
;
Shiting FENG
;
Zhenpeng PENG
;
Ziping LI
;
Junfei MENG
Author Information
- Publication Type:Journal Article
- MeSH: Adenocarcinoma; diagnostic imaging; Adenocarcinoma, Mucinous; diagnostic imaging; Colorectal Neoplasms; diagnostic imaging; Humans; Multimodal Imaging; Positron-Emission Tomography; Retrospective Studies; Tomography, X-Ray Computed
- From: Chinese Journal of Gastrointestinal Surgery 2014;17(3):230-234
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the value of comprehensive application of CT and PET/CT in differential diagnosing mucinous and non-mucinous colorectal adenocarcinoma.
METHODSCT and PET/CT image data of 37 patients with mucinous adenocarcinoma and 50 patients with non-mucinous adenocarcinoma confirmed by pathology in our hospital from January 2010 to December 2012 were analyzed retrospectively. Differences of image were compared between two methods.
RESULTSOn CT, lesion density of pre-contrast, pro-contrast phase and enhancement degree were significantly lower in mucinous adenocarcinoma than those in non-mucinous adenocarcinoma(all P<0.01). Enhancement degree of hypointense area, hypointense area proportion of total lesion, and lymphatic or distant metastasis ratio were significantly higher in mucinous adenocarcinoma than those in non-mucinous adenocarcinoma(all P<0.05). On PET/CT, maximal SUV value of mucinous adenocarcinoma was significantly lower as compared to non-mucinous adenocarcinoma[(8.64±4.34) Bq/L vs. (12.38±5.96) Bq/L, P=0.015].
CONCLUSIONSCT combined with PET/CT provides better valuable information in differential diagnosing between mucinous and non-mucinous colorectal adenocarcinoma and clinical practice.