Copeptin and ischemia modified albumin in early diagnosis and prognosis of myocardial damage in acute organic phosphorus pesticide poisoning.
- Author:
Jing LI
1
;
Jianjun ZHANG
;
Na LI
;
Jia LI
;
Juan LIU
;
Qian LIU
Author Information
- Publication Type:Journal Article
- MeSH: Biomarkers; blood; Early Diagnosis; Glycopeptides; blood; Humans; Organophosphate Poisoning; diagnosis; Pesticides; poisoning; Prognosis; Serum Albumin; Serum Albumin, Human
- From: Journal of Southern Medical University 2015;35(3):459-462
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the value of combined detection of copeptin and ischemia modified albumin (IMA) in early diagnosis and prognostic evaluation of myocardial damage in patients with acute organic phosphorus pesticide poisoning (AOPP).
METHODSA total of 126 AOPP patients were examined for blood copepin and IMA levels and myocardial injury markers within 1 h after admission.
RESULTSCopeptin and IMA levels significantly increased in patients with AOPP compared with those in the control subjects. Copeptin and IMA levels were significantly higher in severe AOPP cases than in mild to moderate cases (P<0.05). Logistic regression analysis showed that increased copeptin and IMA levels and severe complications of AOPP were associated with an increased risk of cardiovascular events.
CONCLUSIONEarly detection of copeptin and IMA levels has important clinical value in early diagnosis and prognostic evaluation of myocardial damage in patients with AOPP, and their levels are positively correlated with the severity of the condition.
