Splenic autotransplantation combined with lower esophagus transaction in the treatment of hepatic cirrhosis induced portal hypertension.
- Author:
Chang-zhen SHANG
1
;
Ya-jin CHEN
;
Hong-wei ZHANG
;
Lei ZHANG
;
Jun CAO
;
Xiao-xiong PENG
;
Ji-sheng CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Esophagus; surgery; Female; Humans; Hypertension, Portal; etiology; surgery; Liver Cirrhosis; complications; Male; Middle Aged; Spleen; transplantation; Transplantation, Autologous; Treatment Outcome; Young Adult
- From: Chinese Journal of Surgery 2009;47(2):83-85
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the therapeutic effect of splenic autotransplantation combined with lower esophagus transaction anastomosis in the treatment of liver cirrhosis induced portal hypertension.
METHODSThirty-six patients admitted from January 2003 to December 2006 were randomly divided into splenic autotransplantation group undergoing splenic autotransplantation after splenectomy combined with lower esophagus transaction anastomosis, and splenectomy group only undergoing splenectomy combined with lower esophagus transaction anastomosis. The general conduction, splenic scanning, liver function, and the level of serum Tuftsin and IgM of each patient were observed before and after operation.
RESULTSThe levels of Tuftsin and IgM in splenic autotransplantation group were significant higher than that of splenectomy group 2 months after the operation, and the liver function showed no significant difference between these two groups. Splenic tissue was detected in the retroperitoneal space by 99mTc-DRBC 2 months after operation.
CONCLUSIONSSplenic autotransplantation combined with lower esophagus transaction anastomosis is a safe and effective treatment strategy for patients with liver cirrhosis induced portal hypertension, and the spleen tissue transplanted into the retroperitoneal space can partially preserve the immune function.
