Chronic Cutaneous Lupus Erythematosus in Two Sisters.
- Author:
Seung Goo KANG
1
;
Chang Woo LEE
;
Sung Soo JUNG
Author Information
1. Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Chronic cutaneous lupus erythematosus;
Sisters
- MeSH:
Alopecia;
Cicatrix;
Connective Tissue;
Constitution and Bylaws;
Humans;
Immunogenetics;
Korea;
Lupus Erythematosus, Cutaneous*;
Mixed Connective Tissue Disease;
Scalp;
Siblings*
- From:Korean Journal of Dermatology
1997;35(6):1263-1267
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Scalp involvements occur in 30-60% of patients with chronic cutaneous lupus erythematosus (CCLE), and may result in irreversible cicartricial alopecia due to follicular destructions. The pathogenesis of CCLE is consiclered to be multifactorial; relevant factors would be immunogenetic, hormonal, and environmental ir fluences. Perhaps, the immunogenetic factors may be more important. We report a case of two sisters who had superficial scarring alopecia on the scalp, in the constitutions of underlying mixed connective tissue disease (MCTD) and undifferentiated connective tissue syndrome (UCTS), respectively. This sister-CCLE case is regarded to be the first report among familial CCLE in Korea.
