Chemical constituents from roots and rhizomes of Panax ginseng cultivated in Jilin province.
- Author:
Hong-Ping WANG
1
;
Xin-Bao YANG
2
;
Xiu-Wei YANG
3
;
Jian-Xun LIU
2
;
Ying-Ping WANG
4
;
Lian-Xue ZHANG
5
Author Information
1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. sungirl9626@163.com
2. Xiyuan Hospital, China Academy of Chinese Sciences, Beijing 100091, China.
3. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
4. Institute of Special Wild Economic Animals and Plants Science, Chinese Academy of Agricultural Sciences, Changchun 130122, China.
5. College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
- Publication Type:Journal Article
- MeSH:
China;
Drugs, Chinese Herbal;
chemistry;
Ginsenosides;
chemistry;
Molecular Structure;
Panax;
chemistry;
growth & development;
Plant Roots;
chemistry;
growth & development;
Sapogenins;
chemistry;
Spectrometry, Mass, Electrospray Ionization
- From:
China Journal of Chinese Materia Medica
2013;38(17):2807-2817
- CountryChina
- Language:Chinese
-
Abstract:
The chemical constituents of the roots and rhizomes of Panax ginseng were systematically investigated by various column chromatographic methods including Amberlite XAD-4 macroporous adsorptive resins and silica gel as well as high-performance liquid chromatography, and their chemical structures were identified by physico-chemical properties and spectral analyses. Twenty-eight compounds were isolated from the 70% ethanolic-aqueous extract and identified as koryoginsenoside R1 (1), ginsenoside Rg1 (2), ginsenoside Rf (3), notoginsenoside R2 (4), ginsenoside Rg2 (5), notoginsenoside Fe (6), ginsenjilinol (7), ginsenoside Re5 (8), noto-ginsenoside N (9), notoginsenoside R1 (10), ginsenoside Re2 (11), ginsenoside Re1 (12), ginsenoside Re (13), ginsenoside Rs2 (14), ginsenoside Ro methyl ester (15), ginsenoside Rd (16), ginsenoside Re3 (17), ginsenoside Re4 (18), 20-gluco-ginsenoside Rf (19), ginsenoside Ro (20), ginsenoside Rc (21), quinquenoside-R1 (22), ginsenoside Ra2 (23), ginsenoside Rb1 (24), ginsenoside Ra1 (25), ginsenoside Ra3 (26), ginsenoside Rb2 (27), and notoginsenoside R4 (28). All isolated compounds are 20 (S) -protopanaxadiol or protopanaxatriol type triterpenoid saponins. Compound 1 was isolated from the roots and rhizomes of P. ginseng cultivated in Jilin province for the first time and compound 6 was isolated from the roots and rhizomes of P. ginseng for the first time. The 1H-NMR data of compounds 6, 14 and 19 were assigned for the first time.
