A Case of Intestinal Neuronal Dysplasia.
- Author:
Se Young KIM
1
;
Yon Ho CHOE
;
Jeong Kee SEO
;
In One KIM
;
Chong Jai KIM
Author Information
1. Department of pediatrics, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Intestinal neuronal dysplasia;
Chronic idiopathic intestinal pseudo-obstructiori syndrome
- MeSH:
Abdominal Pain;
Child, Preschool;
Contrast Media;
Diagnosis;
Dilatation;
Ganglia;
Humans;
Hyperplasia;
Ileostomy;
Intestinal Obstruction;
Intestinal Pseudo-Obstruction;
Intestines;
Laparotomy;
Male;
Myenteric Plexus;
Neurons*;
Pathology;
Vomiting
- From:Journal of the Korean Pediatric Society
1996;39(8):1151-1157
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intestinal neuronal dysplasia(IND) is a disease characterized clinically by symptoms of intestinal obstruction and pathologically by hyperplasia of the submucosal and myenteric plexuses with formation of giant ganglia. Chronic intestinal pseudo-obstruction is a clinical diagnosis, composed of myopathic form and neuropathic form, and normal intestinal histology. Intestinal neuronal dysplasia is a neuropathic form of chronic intestinal pseudo-obstruction. The clinical presentation and the course of IND is very variable. We experienced a case of intestinal neuronal dysplasia in a 5 year-old boy who had suffered from recurrent abdominal pain and vomiting for 3 years. Small bowel series showed multiple intestinal dilatations and delayed excretion of contrast media. He underwent exploratory laparotomy. However no mechanical causes for markedly dilated intestine were found and he received loop ileostomy. However, he suffered from recurrent vomiting and abdominal pain. So, he received repair-operaton. The pathology of surgical specimen showed hyperplasia of the submucosal and myenteric plexuses with giant ganglia. We report this case with a brief review of the related literatures.
