A Case of Combined Congenital Deficiency of Factor V and Factor VIII.
- Author:
Kue Chang CHO
1
;
Soo Kyung LEE
;
Il Kyung KIM
;
Ho SUNG
;
Chang Hee CHOI
Author Information
1. Department of Pediatrics, Seoul Adventist Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Bleeding disorders;
Factor V deficiency;
Factor VIII deficiency;
Hemorrhagic disease of newborn
- MeSH:
Blood Coagulation;
Factor V Deficiency;
Factor V*;
Factor VIII*;
Hemophilia A;
Hemorrhage;
Humans;
Male;
Partial Thromboplastin Time;
Prothrombin Time;
Tooth Extraction;
Vitamin K Deficiency Bleeding
- From:Journal of the Korean Pediatric Society
1996;39(8):1162-1167
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hemorrhagic disease of newborn by combined blood clotting factor deficiencies is very rare. Combined deficiency of factor V and factor VIII is the most common form among these cases, and inherited by autosomal recessive trait. Clinical findings are easy bruising, post-traumatic bleeding and bleeding after tooth extractions, and the main laboratory findings are prolonged partial thromboplastin time (PTT) and prothrombin time (PT) that are different from hemophilia A only with prolonged PTT. We experienced a case of combined congenital deficiency of factor V and factor VIII in a 1-day-old boy. We report the case with brief review of literature.
