Experimental research on non-invasive near-infrared detection of early hepatocirrhosis.
- Author:
Xiaofang ZHANG
1
;
Jianjun LIU
;
Zeping XIE
Author Information
1. Department of Preventative Medicine, Yangtze University Jingzhou, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Carbon Tetrachloride;
Carbon Tetrachloride Poisoning;
Early Diagnosis;
Liver;
blood supply;
Liver Cirrhosis;
chemically induced;
diagnosis;
Mice;
Oximetry;
methods;
Oxygen;
blood;
Regional Blood Flow;
Spectroscopy, Near-Infrared;
methods
- From:
Journal of Biomedical Engineering
2005;22(4):795-797
- CountryChina
- Language:Chinese
-
Abstract:
This experiment was carried out to make an exaluation on the non-invasive near-infrared detection of early hepatocirrhosis. The model of early hepatocirrhosis was established by injecting carbon tetrachloride in mice. Blood and oxygen content in liver tissue were detected with Runman System. The undulated forms of blood and oxygen variation were extracted and analyzed under the software MATLAB. Non-invasive near-infrared detection was found to react sensitively to the variation of the blood and oxygen content in the early hepatocirrhosis. The rhythm of the undulated forms of blood and oxygen in the early hepatocirrhosis was irregular. The main frequency peak of auto-power spectrum was found to move back to the rang 1.0-1.5 Hz and multi-peak was seen. These show that the non-invasive near-infrared detection is of some value in detecting early hepatocirrhosis.
