A study on myocardial microcirculation with coronary angiographic impulse response function.
- Author:
Xingxin CHEN
1
;
Bingquan LUO
;
Lei YUE
;
Shanshan HUANG
Author Information
1. China University of Mine and Technique, Xuzhou 221008, China.
- Publication Type:Journal Article
- MeSH:
Coronary Angiography;
Coronary Circulation;
physiology;
Coronary Stenosis;
diagnostic imaging;
physiopathology;
Humans;
Microcirculation;
physiology
- From:
Journal of Biomedical Engineering
2005;22(5):935-939
- CountryChina
- Language:Chinese
-
Abstract:
We have established a digital coronary angiograph-analyzing system on the principle of coronary angiographic impulse response, and combined the system with the quantitative coronary analysis (QCA) for investigating the coronary microcirculation (Tmicro(-1)), the minimal stenotic diameter of coronary (MLD) and coronary hemodynamic parameters (mAP, CFV, Rcor) in 20 patients with coronary stenosis. The results showed the minimal stenotic diameter (MLD) and Tmicro(-1) decreased, with the increase of stenosis of proximal coronary. After successful percutaneous coronary intervention treatment, the Tmicro(-1) increased with the increase of MLD and was in linear correlation with MLD (r = 0.87, P < 0.001). In conclusion, The index Tmicro(-1) detected by coronary digital angiographic impulse response analysis system in combination with CFV and QCA would help to evaluate the level of integrated diagnosis of coronary lesion in regard to anatomy and physiology as well as to macro and microcirculation.
