The Effect of Corticosteoid Treatment on Myopic Regression after Photorefractive Keratectomy.
- Author:
Kyung Ho WOO
1
;
Ki San KIM
Author Information
1. Department of Ophthalmology, College of Medicine, Keimyung, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
Excimer laser;
Myopic regression;
Photorefractive keratectomy;
Corticosteroid
- MeSH:
Adrenal Cortex Hormones;
Dexamethasone;
Follow-Up Studies;
Humans;
Lasers, Excimer;
Photorefractive Keratectomy*;
Prospective Studies;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
1996;37(8):1270-1276
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
With the aim of reversing myopic regression after PRK, the effect of highdose topical corticosteroid in modulating changes in refraction and corneal transparency were assessed prospectively. Seventy-two eyes of 62 patients (mean preoperative SE -6.14D; -2.30 D to -11.50D), demonstrating myopic regression ranging between -0.75D to -5.33D (mean: -1.69D), were treated with 0.1% dexamethasone eye solution five times a day for averaging 2.8 weeks. The age of patient, amount of attempted correction and K-reading did not influenced statistically significantly on myopic regression. Uncorrected visual acuity, mean refraction before reintroducing corticosteroids (mean: 0.58, -1.69D) improved after corticosteroid treatment (mean: 0.85, -0.42D)(p<0.01). Corneal haze changed statistically significant from 0.80 +/- 0.61 to 0.53 +/- 0.40 after steroid treatment(p<0.01). Topical corticosteroid therapy can modulate refractive changes after PRK, appearing to improve myopic regression. However, a long term follow up will be necessary to determine the final refractive outcome of these eyes.
