The effect of semen antisperm antibody on human sperm acrosin activity.
- Author:
Rui-Zhi LIU
1
;
Ying-Li LU
;
Zong-Ge XU
;
Wen-Jing ZUO
;
Ji-Li XIN
;
Zhong-Shan WANG
Author Information
- Publication Type:Journal Article
- MeSH: Acrosin; metabolism; Adult; Autoantibodies; analysis; Case-Control Studies; Humans; Infertility, Male; immunology; Male; Semen; chemistry; Spermatozoa; enzymology; immunology
- From: National Journal of Andrology 2003;9(4):252-253
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo study the effect of antisperm antibody(AsAb) on human sperm acrosin activity.
METHODSAsAb and sperm acrosin activity were measured and analyzed in 3,432 infertile men and 65 fertile volunteers.
RESULTSAsAb positive rate was 10.20% in 3,432 case of male infertility, and 9.37% in 2,882 infertile males who received tests of sperm acrosin activity. Acrosin activity of infertility cases were lower than those of fertile cases(P < 0.001). The comparison between AsAb positive group and AsAb negative group infertility cases showed no significant differences of acrosin activity (P > 0.05). Between normal acrosin activity group and abnormal acrosin activity group, there was no significant difference of AsAb positive rate (P > 0.05).
CONCLUSIONSAntisperm antibody could not affect acrosin activity.
