Advances in sperm membrane antigens.
- Author:
Yi-Feng GE
1
;
Yu-Feng HUANG
Author Information
1. Laboratory of Reproduction & Genetics, Nanjing General Hospital, Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Antigens, Surface;
genetics;
immunology;
Cell Membrane;
immunology;
Cloning, Molecular;
Humans;
Male;
Mice;
Spermatozoa;
immunology;
Vaccines, Contraceptive
- From:National Journal of Andrology
2003;9(4):292-295
- CountryChina
- Language:Chinese
-
Abstract:
A series of sperm membrane antigens, the important molecular markers associated with the program of spermatogenesis and maturation of sperm, which also are for attachment of the physiological mechanism of the sperm-egg interaction and fusion and the pathological changes in the infertility, were reviewed. Some traditional crucial sperm membrane proteins, such as FA-1, PH-20, fertilin, have been cloned and sequenced, and some novel gene which encode new proteins associated with the sperm membrane also have been screened out successively. All of these provided a basement for lucubration of these proteins and the research of the contraception vaccine.
