Infection of Chlamydia trachomatis and apoptosis of spermatogenic cells.
- Author:
Chang-Chun WAN
1
;
Hong WANG
;
Bao-Jin HAO
;
Xue-Jun SHANG
;
Yu-Feng HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Apoptosis; Chlamydia Infections; complications; pathology; Chlamydia trachomatis; Humans; In Situ Nick-End Labeling; Infertility, Male; etiology; Male; Spermatocytes; pathology; Staining and Labeling
- From: National Journal of Andrology 2003;9(5):350-354
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the relationship between infection of Chlamydia Trachomatis(Ct) and apoptosis of spermatogenic cells.
METHODSApoptotic spermatogenic cells were examined by Wright-Giemsa staining and the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate(dUTP)-biotin nick-end labeling(TUNEL) technique.
RESULTSApoptosis rate of Ct infective group was significantly higher than that of normal group(P < 0.01).
CONCLUSIONSCt infection may cause the apoptosis of spermatogenic cells, which affords an objective evidence for illustrating the mechanism of Ct-infection-induced male infertility.
