The relationship between proto-oncogene and testicular function.
- Author:
Hai-Bin KUANG
1
;
Lian FANG
Author Information
1. Department of Physiology, Jiangxi Medical College, Nanchang, Jiangxi 330006, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Gene Expression Regulation, Developmental;
Humans;
Leydig Cells;
cytology;
Male;
Proto-Oncogenes;
physiology;
Sertoli Cells;
cytology;
Spermatogenesis;
genetics;
Testis;
physiology
- From:
National Journal of Andrology
2003;9(5):377-380
- CountryChina
- Language:Chinese
-
Abstract:
Proto-oncogene, the fundamental component of cellular genome, is rarely or finitely expressed in normal conditions, and can regulate cellular proliferation, differentiation and information conduction. Many proto-oncogenes show the temporal and specific expression during spermatogenesis. The expression of some proto-oncogenes reinforces in the growth and development of Sertoli cells and Leydig cells. To explore the relationship between proto-oncogene and testicular function and that between proto-oncogene and regulative factors of testicular function helps to comprehend the regulation of the testicular function at the molecular level.
