Studies and progress of male hormonal contraception.
- Author:
Yu-Gui CUI
1
;
Xing-Hai WANG
;
Jian-Sun TONG
Author Information
1. Key Laboratory, First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China.
- Publication Type:Journal Article
- MeSH:
Androgens;
Animals;
Contraception;
methods;
Contraceptive Agents, Male;
Contraceptives, Oral, Hormonal;
Humans;
Male;
Mice;
Progestins;
Rats;
Sheep
- From:National Journal of Andrology
2003;9(5):381-384
- CountryChina
- Language:Chinese
-
Abstract:
It has become more and more urgent to develop a safe, effective, recoverable and acceptable contraceptive for males. Decades of studies have made much progress on male hormonal contraception, one of the promising contraceptive methods. The principle is based on the suppression of pituitary gonadotropin and intratesticular testosterone, then the suppression of spermatogenesis, and the supplement of androgen to maintain the male characteristics and sexual function. There are many male hormonal contraceptive methods being studied include androgen, androgen combined with progesterone, GnRH antagonists combined with androgen, as well as immunological methods. To develop a safe and convenient androgen preparation with longer action and fewer side effects is also one of the key items of present research in this field.
