The change and implication of epididymis sialic acid following torsing/detorsing testes in rats.
- Author:
Yu-Gang ZHAO
1
;
Xin-Min ZHENG
;
Zhi-Wei YANG
;
Shi-Wen LI
;
Li-Quan HU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Epididymis; chemistry; Male; N-Acetylneuraminic Acid; analysis; Rats; Rats, Sprague-Dawley; Spermatic Cord Torsion; metabolism; Time Factors
- From: National Journal of Andrology 2003;9(6):429-430
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the change and implication of epididymis sialic acid after 24 hours following 2- or 4-hour torsing/detorsing of testes in rats.
METHODSTwenty-four adult male Sprague-Dawley rats were subjected to unilateral 720 degrees testicular torsion for 2 and 4 hours and then repaired. The ischemic epididymides were collected for detecting the content of sialic acid by spectrophotometry.
RESULTSThere was no statistically significant difference between the content of epididymis sialic acid after 24 hours following 2-hour torsing/detorsing of testes and that of the sham group, while significant difference was found between the content of epididymis sialic acid after 24 hours following 4-hours torsing/detorsing of testes and that of sham group.
CONCLUSIONSSialic acidsecreting-function of epididymis can remain normal after one day following 2-hour torsing/detorsing of testes, and be injured after one day following 4-hour torsing/detorsing of testes. The epididymis remains resistant to ischemic damage during testicular ischemia.