Tamsulosin in the treatment of benign prostatic hyperplasia patients with acute urinary retention.
- Author:
Li-Xin HUA
1
;
Hong-Fei WU
;
Yuan-Geng SUI
;
Shuang-Guan CHEN
;
Zheng-Quan XU
;
Wei ZHANG
;
Li-Xin QIAN
Author Information
- Publication Type:Clinical Trial
- MeSH: Acute Disease; Adrenergic alpha-Antagonists; administration & dosage; therapeutic use; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Prostatic Hyperplasia; complications; drug therapy; Sulfonamides; administration & dosage; therapeutic use; Treatment Outcome; Urinary Catheterization; Urinary Retention; complications; drug therapy
- From: National Journal of Andrology 2003;9(7):510-511
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the clinical efficacy of alpha-1 A adrenoceptor antagonist (tamsulosin) in the treatment of benign prostatic hyperplasia (BPH) patients with acute urinary retention.
METHODSSeventy-two BPH patients with acute retention of urine were randomly divided into treatment group and control group of 36 patients each. All the patients were treated with indwelling catheter, oral antibiotics and the patients in treatment group tamsulosin 0.4 mg once a day for 3 days. The catheter was removed after 72 hours of treatment.
RESULTSAfter removal of the catheter, 44% (32/72) of patients voided successfully. The effect rates were 61% (22/36) in the tamsulosin treatment group and 28% (10/36) in the control group(P < 0.01).
CONCLUSIONSTreatment with tamsulosin was effective in raising the success rate of voiding without catheter after an episode of acute urinary retention. The efficacy of treatment was not influenced by the volume of prostate.
