Analysis of risk factors for selective devascularization in patients with portal hypertension.
- Author:
Ya-Juan CAO
1
;
Min XIE
;
Shan-Hua BAO
;
Yi-Ming PAN
;
Bi-Yun XU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Female; Humans; Hypertension, Portal; surgery; Logistic Models; Male; Middle Aged; Portasystemic Shunt, Surgical; adverse effects; methods; Postoperative Complications; etiology; Prognosis; Retrospective Studies; Risk Factors; Young Adult
- From: Chinese Journal of Surgery 2008;46(1):18-20
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the risk factors for selective devascularization in patients with portal hypertension.
METHODSThe clinical data of 160 patients with portal hypertension underwent selective devascularization were retrospectively analyzed. All the patients were divided into high-risk group and low-risk group according to the postoperative complications. Thirty-two clinical factors were analyzed using logistic regression.
RESULTSSingle-factor analysis showed that history of jaundice, Child-Turcotte-Pugh classification, total bilirubin (before the operation), prolongation of prothrombin time, pre-operative free portal pressure, ascites, leukocyte count (1 week after the operation) and hemoglobin (1 week after the operation) were significantly different between the high-risk group and low-risk group (P < 0.05). Logistic regression analysis showed that decrease of free portal pressure, total bilirubin (before the operation), prolongation of prothrombin time, ascites, leukocyte count (1 week after the operation) and hemoglobin (1 week after the operation) were still significantly different between the two groups (chi2 = 53.337, P < 0.01).
CONCLUSIONSThe risk factors of selective devascularization in patients with portal hypertension are decrease of free portal pressure, pre-operative total bilirubin, prolongation of prothrombin time, ascites, post-operative leukocyte count and hemoglobin.