The clinical analysis of 54 cases for the surgical treatment of pulmonary embolism.
- Author:
Hui-Li GAN
1
;
Jian-Qun ZHANG
;
Zhao-Guang ZHANG
;
Qi-Wen ZHOU
;
Yi LUO
;
Jun-Sheng MU
;
Sheng-Xun WANG
;
Si-Hong ZHENG
;
Xiang-Feng ZHANG
;
Shuang LIU
;
Guang-Fa ZHU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Embolectomy; methods; Endarterectomy; methods; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Pulmonary Artery; surgery; Pulmonary Embolism; pathology; surgery; Retrospective Studies; Treatment Outcome; Young Adult
- From: Chinese Journal of Surgery 2008;46(1):48-51
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the results of surgical procedures for pulmonary embolism.
METHODSFifty-four patients of pulmonary embolism received surgical treatment from October 1994 to June 2007, of which 9 were acute pulmonary embolism underwent pulmonary embolectomy and 45 patients were chronic thromboembolic pulmonary hypertension (CTEPH) underwent pulmonary thromboendarterectomy.
RESULTSThe mortality rate was 44.4% in acute pulmonary embolism group and 13.3% in CTEPH group (P < 0. 05). Thirteen patients had residual pulmonary hypertension and 23 patients had severe pulmonary reperfusion injury postoperatively. The pulmonary artery systolic pressure changed from (89.4 +/- 36.3) mm Hg (1 mm Hg =0.133 kPa) preoperative to (55.6 +/- 22.4) mm Hg postoperative. The pulmonary vascular resistance changed from (89. 7 +/- 56.7) kPa L(-1) S(-1) preoperative to (38.9 +/- 31.1) kPa L(-1) S(-1) postoperative. The arterial partial pressure of oxygen changed from (52. 3 +/- 6.7 ) mm Hg preoperative to (87.6 +/- 6.5) mm Hg postoperative. The arterial oxygen saturation changed from (88.9 +/- 4.5)% preoperative to (95.3 +/- 2.8 )% postoperative (P < 0.05). With the follow-up of (41.8 +/- 36.4) months, there were 4 patients died. According to NYHA, there were 28 patients for class I , 10 patients for class II and 2 patients for class III. According to Kaplan-Meier survival curve, the 3-year, 4-year, 5-year and 8-year survival rate were (97.1 +/- 2.8 )%, (94.0 +/- 4.1)%, (90.8 +/- 5.2)% and (85.0 +/- 7.3)% respectively. Linear rate of bleeding and thromboembolic related to anticoagulation were 0. 63% patient-years and 0. 62% patient-years respectively.
CONCLUSIONSThe operational mortality of acute pulmonary embolism is significantly higher than CTEPH, and the mid-long term survival rate is agreeable and the complication rate related to anticoagulation is relatively low.