Infection status and virulent genes of Aeromonas in diarrhea patients in Pudong New Area, Shanghai.

Wenqing Wang; Duochun Wang; Linying Zhu; Yifei FU; Lipeng Hao; Xuebin XU; Jinghua SU; Huiqin FU; Chuchu YE; Qiao Sun; Yingjie Zheng

Return

Infection status and virulent genes of Aeromonas in diarrhea patients in Pudong New Area, Shanghai.

Author: Wenqing WANG ¹ ; Duochun WANG ² ; Linying ZHU ¹ ; Yifei FU ³ ; Lipeng HAO ¹ ; Xuebin XU ⁴ ; Jinghua SU ¹ ; Huiqin FU ¹ ; Chuchu YE ³ ; Qiao SUN ³ ; Yingjie ZHENG ⁵
Author Information

1. Department of Microbiology of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China.
2. State Key Laboratory for Communicable Disease Control and Prevention, Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
3. Department of Infectious Disease Control and Prevention and Disinfection Management Section of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China.
4. Department of Microbiology of Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.
5. Key Laboratory of Public Health Safety of the Ministry of Education, Department of Public Health Microbiology, Fudan University School of Public Health, Shanghai 200032, China.
Publication Type:Journal Article
MeSH: Aeromonas; genetics; Aeromonas hydrophila; genetics; China; epidemiology; Diarrhea; microbiology; Gram-Negative Bacterial Infections; epidemiology; microbiology; Humans; Seasons; Virulence; genetics; Young Adult
From: Chinese Journal of Epidemiology 2016;37(3):402-405
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo investigate the infection status and virulent genes of Aeromonas in patients with acute diarrhea in Pudong New Area, Shanghai.
METHODSIn 2012, stool samples were collected from diarrhea patients in 12 sentinel hospitals in Pudong for the detections of 13 pathogens causing diarrhea, and the detections of 5 diarrhea related virulent genes were conducted for Aeromonas isolates.
RESULTSA total of 101 patients were infected with Aeromonas in 2533 patients (4.0%). A total of 101 Aeromonas strains were isolated, including 17 Aeromonas hydrophila strains (18.8%), 44 Aeromonas veronii biovar sobria strains (52.5%) and 12 Aeromonas caviae strains (29.7%). And 44 coinfections with other pathogens were detected. Aeromonas infection mainly occurred in summer and in people aged ≥20 years. Among the patients infected with Aeromonas, 71 (70.3%) had watery diarrhea, 20 (19.8%) had vomiting and 11 (10.9%) had fever. Virulent genes detection showed that 95.0% of the Aeromonas. strains carried virulent genes, and the detection rates of hlyA, aerA, act, alt, and ast genes were 5.9%, 6.9%, 67.3%, 42.6% and 13.9%, respectively.
CONCLUSIONSHigh incidence of Aeromonas infection was found in the patients with acute diarrhea in Pudong, and a high proportion of coinfections with other pathogens was detected too. Most Aeromonas strains carried virulent genes, and the distribution varied.