Involvement of sympathetic nervous system in the pathogenesis of hypertension.
10.3760/cma.j.issn.1003-9406.2013.05.012
- Author:
Wenxi JIANG
1
;
Xue-zhi ZHANG
;
Ming-liang GU
Author Information
1. Department of Hypertension, Xinjiang Medical University Affiliated Fifth Hospital, Urumqi, Xinjiang 830011, P. R. China. Email: guml@big.ac.cn.
- Publication Type:Journal Article
- MeSH:
Animals;
Hormones;
metabolism;
Humans;
Hypertension;
genetics;
metabolism;
pathology;
Sympathetic Nervous System;
metabolism;
pathology
- From:
Chinese Journal of Medical Genetics
2013;30(5):565-569
- CountryChina
- Language:Chinese
-
Abstract:
Sustained activation of sympathetic nervous system in response to stimulation of a wide variety of stress factors is an independent risk factor for the development of essential hypertension. Adrenal hormone biosynthesis pathway as an important part of the sympathetic nervous system consists of hormones, neurotransmitters, receptors, and a variety of synthases and invertases. In this article, we have systematically reviewed research progresses made in elucidating the interactions between genes of the adrenal hormone biosynthesis pathway and stress factors in the pathogenesis of essential hypertension.
