Necessity of splenectomy in radical resection of gastric cancer: a meta-analysis.
- Author:
Jie DING
1
;
Guo-qing LIAO
;
Zhong-min ZHANG
;
Yang PAN
;
Qing NI
;
Lang-song HAO
;
Run-hua WANG
;
Dong-miao LI
Author Information
- Publication Type:Journal Article
- MeSH: Gastrectomy; Humans; Lymph Node Excision; Splenectomy; Stomach Neoplasms; pathology; surgery
- From: Chinese Journal of Gastrointestinal Surgery 2011;14(2):120-124
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the necessity of splenectomy in radical resection of gastric cancer.
METHODSTwelve studies comparing outcomes after radical resection of gastric cancer with or without splenectomy were identified. Both fixed effect model and random effect model were used.
RESULTSThere were 2628 patients in total. There were significant differences in complications between splenectomy group and spleen-preserving group(OR=1.91, 95% CI:1.28-2.87, P<0.05), while no significant difference in 5-year survival rate was noticed(HR=0.90, 95% CI:0.73-1.11, P>0.05).
CONCLUSIONRadical resection of gastric cancer combined with splenectomy is not associated with improved survival but increased postoperative complications.
