Lipid metabolic disorders in type 2 diabetics
- Author:
Luong Kim Nguyen
- Publication Type:Journal Article
- Keywords:
diabete
- MeSH:
Diabetes Mellitus, Type 2;
Lipids
- From:Journal of Practical Medicine
2000;383(6):20-23
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
This study was carried out on 91 participants. They were divided into 2 groups: 60 patients with type 2 diabetic mellitus, aged more than 40 years were involved in one group and 31 non-diabetics matched by age were served as control group. Symptoms and complications of diabetes were determined by physical examination. Waist and hip circumferences were measured and BMI and waist to hip ratio was calculated. Fasting blood samples were collected and analyzed for glucose, total cholesterol, triglycerid, HDL-C, Apo A1 and Apo A2. The total cholesterol to HDL-C and Apo A1 to Apo A2 ratios were calculated from the result of lipid parameters. The findings of research suggested that the lipoprotein profile in type 2 diabetics was characterized by elevation of serum triglyceride, lowering in HDL-C and increasing in total cholesterol to HDL-C ratio. Most of patients a moderate BMI (53.44%) but the central obesity was common (63.71%). The waist circumference was positively correlated with triglyceride concentration (r = 0.3). The waist to hip ratio was negatively correlated with HDL-C concentration (r = -0.45) and positively correlated with total cholesterol to HDL-C ratio (r = 0.3).
