Changes of sleep architecture in children with obstructive sleep apnea syndrome.
- Author:
Da-bo LIU
1
;
Li-feng ZHOU
;
Jian-wen ZHONG
;
Jie WANG
Author Information
- Publication Type:Journal Article
- MeSH: Child; Child, Preschool; Female; Humans; Male; Monitoring, Ambulatory; Polysomnography; Severity of Illness Index; Sleep Apnea, Obstructive; classification; pathology; physiopathology; Sleep Stages; physiology
- From: Chinese Journal of Pediatrics 2004;42(4):284-286
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore how obstructive sleep apnea syndrome (OSAS) affects children's sleep architecture.
METHODSEighty-three children with OSAS were reviewed; every patient was monitored with polysommography for 7 hours at night for 11 parameters, including the number of arousal, snoring index, nadir O(2) desaturation, stage I %, stage II %, show wave sleep (SWS)% and rapid eye movement (REM)%. The basis for diagnosis of OSAS was the widely accepted pediatric diagnostic criteria of apnea/hypopnea index, apnea/ hypopnea index of > 1 episode/hour, nadir O(2) desaturation < 92%. Sleep was scored manually according to the standard set by Rechtschaffen.
RESULTSIn OSAS group, the number of arousal was 22.5 +/- 1.4, snoring index was 70.6 +/- 16.5, and/or SaO(2) was (73.8 +/- 1.9)%. OSAS group had increased stage I : (45.8 +/- 2.0)% vs. (2.3 +/- 1.1)%, t = 22.46, P < 0.01 and decreased stage II : (23.9 = 1.7)% vs (47.9 = 4.4)%, t = - 14.18, P < 0.01, SWS (15.6 +/- 1.8)% vs. (21.1 +/- 5.0)%, t = - 3.123, P < 0.01, REM (14.7 +/- 1.5)% VS. (28.2 +/- 4.1)%, T = -8.923, p < 0.01.
CONCLUSIONThe severity of OSAS relates to changes of sleep architecture in children. Intermittent nocturnal hypoxia secondary to apnea/hypopnea, and frequent electroencephalogram arousals from sleep may result in significant sleep fragmentation. Children with OSAS had learning problems and failure to thrive.
