The treatment of the acute myeloid leukemia by guideline of 7-3-5 (CDE: cytarabine, daurorubicin, etoposide).
- Author:
Be Van Tran
- Publication Type:Journal Article
- Keywords:
acute myeloid leukemia
- MeSH:
Leukemia, Myelocytic, Acute;
therapy;
therapeutics
- From:Journal of Vietnamese Medicine
2001;267(12):5-9
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Induction chemotherapy of 7-3-5 protocol (cytarabine, daunorubicin, etoposide) in acute myeloid leukemia. Between October 1998 and October 1999, 10 patients with AML (4M, 6F, median age 31) were treated with induction chemotherapy of 7-3-5 protocol at the blood transfusion and hematology center, HCM city. A complete remission was achieved in 9 of 10 patients. 1 patient died from transfusion- associated graft- versus- host disease. The median time to recover ANC> 05x 109/1 and platelets> 20x109/1 were 16 days. Oral mucositis was mild in 2 patients. 7-3-5 protocol may be more effective than 7-3 protocol in response rate and prolonged remission but toxicity was similar.
