Clinical study of idiopathic dilated cardiomyopathy complicated by left ventricular aneurysm.
- Author:
Shu-dong XIA
1
;
Bi-feng WU
;
Jian-mei JIN
;
Jun-zhu CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Arrhythmias, Cardiac; etiology; Cardiomyopathy, Dilated; complications; pathology; physiopathology; Female; Heart Aneurysm; complications; pathology; physiopathology; Humans; Male; Middle Aged; Retrospective Studies
- From: Chinese Journal of Cardiology 2009;37(4):314-319
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo examine the hemodynamic and electrophysiological influence of left ventricular aneurysm (LVA) formation in patients with idiopathic dilated cardiomyopathy (IDCM).
METHODSAll hospital records were retrospectively reviewed from IDCM patients admitted to our hospital between 2003 and 2008. Patients with coronary angiography evidenced ischemic cardiomyopathy were excluded. IDCM patients with LVA (I + L) diagnosed by left ventriculography were enrolled. Twelve age-, gender- and left-ventricular-diameter- matched patients with IDCM without LVA served as control group (I - L).
RESULTSSix out of 998 patients with IDCM were confirmed to have LVA (0.60%). The LV peak-systolic pressure was higher in the I + L group than in I - L group [ (130 +/- 10) mm Hg (1 mm Hg = 0.133 kPa) vs. (117 +/-9) mm Hg, P < 0.05]. The LV end-diastolic volume was significantly larger in the I + L group than in I-L group[ (272 +/- 57) ml vs. (207 +/- 60) ml, P < 0.05]. The LV ejection fraction was slightly lower in the I + L group than in I - L group [ (27 +/- 9)% vs. (35 +/- 6)%, P = 0. 09]. Ventricular arrhythmia occurred more frequently in I + L group than in I - L group.
CONCLUSIONLVA formation in IDCM was a rare phenomenon. IDCM patients with LVA seem to have higher LV peak-systolic pressure, larger end-diastolic volume, worse LV systolic function and more frequent ventricular arrhythmia than those without LVA.
